Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms
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چکیده
منابع مشابه
Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms.
BACKGROUND Congenital atrial standstill has been linked to SCN5A. Incomplete penetrance observed in atrial standstill has been attributed in part to the digenic inheritance of polymorphisms in the atrial-specific gap junction connexin 40 (Cx40) in conjunction with an SCN5A mutation. OBJECTIVES The purpose of this study was to determine the clinical and biophysical characteristics of a novel S...
متن کاملA novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation.
OBJECTIVES This study describes a novel heterozygous gain-of-function mutation in the cardiac sodium (Na+) channel gene, SCN5A, identified in a Japanese family with lone atrial fibrillation (AF). BACKGROUND SCN5A mutations have been associated with a variety of inherited arrhythmias, but the gain-of-function type modulation in SCN5A is associated with only 1 phenotype, long-QT syndrome type 3...
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A 6-year-old male crossbred dog was referred to the Veterinary Medical Teaching Hospital of Islamic Azad University of Karaj with the history of abdominal distention, rectal tenesmus and stranguria. Abdominal radiographs and ultrasonography indicated large distended urinary bladder and prostatic enlargement. ECG showed temporary episodes of atrial standstill. The only abnormalities detected by ...
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2005
ISSN: 1547-5271
DOI: 10.1016/j.hrthm.2005.06.032